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1

A region C-terminal to the proline-rich core of p47phox regulates activation of the phagocyte NADPH oxidase by interacting with the C-terminal SH3 domain of p67phox

Kazuhito Mizuki, Ryu Takeya, Futoshi Kuribayashi, Ikuo Nobuhisa, Daisuke Kohda, Hiroyuki Nunoi, Koichiro Takeshige, Hideki Sumimoto

Journal:

Archives of Biochemistry and Biophysics

Year:

2005

Language:

english

File:

PDF, 444 KB

english, 2005

2

Leopard Skin–Like Colonic Mucosa

Obayashi, Naho, Arai, Katsuhiro, Nakano, Natsuko, Mizukami, Tomoyuki, Kawai, Toshinao, Yamamoto, Shojiro, Shimizu, Hirotaka, Nunoi, Hiroyuki, Shimizu, Toshiaki, Tang, Julian, Onodera, Masafumi

Journal:

Journal of Pediatric Gastroenterology & Nutrition

Year:

2016

Language:

english

File:

PDF, 18.40 MB

english, 2016

3

A hot-spot mutation in CDC42 (p.Tyr64Cys) and novel phenotypes in the third patient with Takenouchi-Kosaki syndrome

Motokawa, Midori, Watanabe, Satoshi, Nakatomi, Akiko, Kondoh, Tatsuro, Matsumoto, Tadashi, Morifuji, Kanako, Sawada, Hirotake, Nishimura, Toyoki, Nunoi, Hiroyuki, Yoshiura, Koh-ichiro, Moriuchi, Hiroy

Journal:

Journal of Human Genetics

Year:

2018

Language:

english

File:

PDF, 600 KB

english, 2018

4

C-MYC rearrangement may induce an aggressive phenotype in anaplastic lymphoma kinase positive anaplastic large cell lymphoma: Identification of a novel fusion gene ALO17/C-MYC

Hiroshi Moritake, Hidemi Shimonodan, Kousuke Marutsuka, Sachiyo Kamimura, Hitomi Kojima, Hiroyuki Nunoi

Journal:

American Journal of Hematology

Year:

2011

Language:

english

File:

PDF, 1.44 MB

english, 2011

5

Acute megakaryoblastic leukemia and severe pulmonary fibrosis in a child with down syndrome: Successful treatment with ultra low-dose cytarabine using GATA1 mutation to monitor minimal residual disease

Hiroshi Moritake, Ai Yamada, Yasuhiro Kimoto, Daisuke Sawa, Hidemi Shimonodan, Hiroyuki Nunoi

Journal:

American Journal of Hematology

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

6

Drug-selected co-expression of P-glycoprotein and gp91 in vivo from an MDR1-bicistronic retrovirus vector Ha-MDR-IRES-gp91

Yoshikazu Sugimoto, Satomi Tsukahara, Shigeo Sato, Mutsumi Suzuki, Hiroyuki Nunoi, Harry L. Malech, Michael M. Gottesman, Takashi Tsuruo

Journal:

The Journal of Gene Medicine

Year:

2003

Language:

english

File:

PDF, 254 KB

english, 2003

7

Interleukin 12 and myeloperoxidase (MPO) in Vietnamese children with acute respiratory distress syndrome due to Avian influenza (H5N1) infection

Thuy T.B. Phung, San T. Luong, Shoji Kawachi, Hiroyuki Nunoi, Liem T. Nguyen, Toshinori Nakayama, Kazuo Suzuki

Journal:

Journal of Infection

Year:

2011

Language:

english

File:

PDF, 385 KB

english, 2011

8

X-CGDbase: a database of X-CGD-causing mutations

Dirk Roosl, John T. Curnutte, Johann Peter Hossle, Yu Lung Lau, Tadashi Ariga, Hiroyuki Nunoi, Mary C. Dinauer, Manfred Gahr, Anthony W. Segal, Peter E. Newburger, Mauro Giacca, Nicholas H. Keep, Rob

Journal:

Immunology Today

Year:

1996

Language:

english

File:

PDF, 778 KB

english, 1996

9

Duplication (22)(q11.22-q11.23) without coloboma and cleft lip or palate

TOHRU SONODA, KEIICHIRO KOUNO, KAZUMI SAWADA, JUNICHI TAKAGI, HIROYUKI NUNOI, NAOKI HARADA, NAOMICHI MATSUMOTO

Journal:

Pediatrics International

Year:

2003

Language:

english

File:

PDF, 502 KB

english, 2003

10

Cytomegalovirus infection mimicking juvenile myelomonocytic leukemia showing hypersensitivity to granulocyte–macrophage colony stimulating factor

Hiroshi Moritake, Toshio Ikeda, Atsushi Manabe, Sachiyo Kamimura, Hiroyuki Nunoi

Journal:

Pediatric Blood & Cancer

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

11

A disease with immune deficiency, skin abscesses, pancytopenia, abnormal bone marrow karyotype, and increased sister chromatid exchanges: An autosomal recessive chromosome instability syndrome?

Yasuhide Yanabe, Hiroyuki Nunoi, Hiroyuki Tsuchiya, Shigenori Higuchi, Izumi Akaboshi, Akihiko Kitano, Masao S. Sasaki, Ichiro Matsuda

Journal:

Journal of Human Genetics

Year:

1990

Language:

english

File:

PDF, 688 KB

english, 1990

12

Neutrophil Cytoskeletal Disease

Hiroyuki Nunoi, Tsuyoshi Yamazaki, Shiro Kanegasaki

Journal:

International Journal of Hematology

Year:

2001

Language:

english

File:

PDF, 444 KB

english, 2001

13

Statistical and mutational analysis of chronic granulomatous disease in Japan with special reference to gp91-phoxand p22-phoxdeficiency

Fuminari Ishibashi, Hiroyuki Nunoi, Fumio Endo, Ichiro Matsuda, Shiro Kanegasaki

Journal:

Year:

2000

Language:

english

File:

PDF, 151 KB

english, 2000

14

Mutations of the CD40 ligand gene in 13 Japanese patients with X-linked hyper-IgM syndrome

Shigeaki Nonoyama, Mitsunobu Shimadzu, Hano Toru, Kuniaki Seyama, Hiroyuki Nunoi, Michael Neubauer, Jun-ichi Yata, Hans D. Ochs

Journal:

Year:

1997

Language:

english

File:

PDF, 65 KB

english, 1997

15

Drug-selected complete restoration of superoxide generation in Epstein-Barr virus-transformed B cells from p47phox-deficient chronic granulomatous disease patients by using a bicistronic retrovirus vector encoding a human multi-drug resistance gene (MDR1) and the p47phoxgene

Mayumi Iwata, Hiroyuki Nunoi, Ichiro Matsuda, Shiro Kanegasaki, Takashi Tsuruo, Y. Sugimoto

Journal:

Year:

1998

Language:

english

File:

PDF, 98 KB

english, 1998

16

Successful Treatment with Infliximab for Inflammatory Colitis in a Patient with X-linked Anhidrotic Ectodermal Dysplasia with Immunodeficiency

Tomoyuki Mizukami, Megumi Obara, Ryuta Nishikomori, Tomoki Kawai, Yoshihiro Tahara, Naoki Sameshima, Kousuke Marutsuka, Hiroshi Nakase, Nobuhiro Kimura, Toshio Heike, Hiroyuki Nunoi

Journal:

Journal of Clinical Immunology

Year:

2012

Language:

english

File:

PDF, 812 KB

english, 2012

17

Successful treatment of chronic granulomatous disease with fludarabine-based reduced-intensity conditioning and unrelated bone marrow transplantation

Daiichiro Hasegawa, Masako Fukushima, Yuki Hosokawa, Hiroki Takeda, Keiichiro Kawasaki, Tomoyuki Mizukami, Hiroyuki Nunoi, Hiroshi Ochiai, Tomohiro Morio, Yoshiyuki Kosaka

Journal:

International Journal of Hematology

Year:

2008

Language:

english

File:

PDF, 167 KB

english, 2008

18

Cell adhesion markedly increases lucigenin-enhanced chemiluminescence of the phagocyte NADPH oxidase

Futoshi Kuribayashi, Satoru Tsuruta, Tsuyoshi Yamazaki, Hiroyuki Nunoi, Shinobu Imajoh-Ohmi, Shiro Kanegasaki, Michio Nakamura

Journal:

Year:

2008

Language:

english

File:

PDF, 295 KB

english, 2008

19

Apoptosis under hypercytokinemia is a possible pathogenesis in influenza-associated encephalopathy

Hiroyuki Nunoi, Maria Regina Mercado, Tomoyuki Mizukami, Kenji Okajima, Tsuneo Morishima, Hiroshi Sakata, Shinichi Nakayama, Seiji Mori, Masatoshi Hayashi, Hiromi Mori, Seiichi Kagimoto, Shiro Kaneg

Journal:

Pediatrics International

Year:

2005

Language:

english

File:

PDF, 92 KB

english, 2005

20

A novel mutation of the PHKA2 gene in a patient with X-linked liver glycogenosis type 1

Fumio Hidaka, Hirotake Sawada, Misayo Matsuyama, Hiroyuki Nunoi

Journal:

Pediatrics International

Year:

2005

Language:

english

File:

PDF, 348 KB

english, 2005

21

Hazards of early BCG vaccination: BCGitis in a patient with chronic granulomatous disease

HISASHI KAWASHIMA, DAISUKE HASEGAWA, MIKAGE NAKAMURA, SHINJI MOCHIZUKI, YASUYO KASHIWAGI, SHIGEO NISHIMATA, SATOSHI SATO, MASATO SASAMOTO, KOUJI TAKEKUMA, AKINORI HOSHIKA, HIROYUKI NUNOI

Journal:

Pediatrics International

Year:

2007

Language:

english

File:

PDF, 84 KB

english, 2007

22

Successful bone marrow transplantation in chronic granulomatous disease

Mizuka Miki, Atsushi Ono, Ayumi Awaya, Shinichiro Miyagawa, Rie Onodera, Emi Kurita, Asako Hiraoka, Fumio Hidaka, Tomoyuki Mizukami, Hiroyuki Nunoi, Masao Kobayashi

Journal:

Pediatrics International

Year:

2009

Language:

english

File:

PDF, 211 KB

english, 2009

23

Structural organization of the gene for CD40 ligand: molecular analysis for diagnosis of X-linked hyper-IgM syndrome

Mitsunobu Shimadzu, Hiroyuki Nunoi, Hiroshi Terasaki, Rukako Ninomiya, Mayumi Iwata, Shiro Kanegasaka, Ichiro Matsuda

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1995

Language:

english

File:

PDF, 626 KB

english, 1995

24

Newly established Askin tumor cell line and overexpression of focal adhesion kinase in Ewing sarcoma family of tumors cell lines

Hiroshi Moritake, Tohru Sugimoto, Hiroshi Kuroda, Fumio Hidaka, Yukiko Takahashi, Masazumi Tsuneyoshi, Mitsuaki A. Yoshida, Qingping Cui, Kensuke Akiyoshi, Tatsuro Izumi, Hiroyuki Nunoi

Journal:

Cancer Genetics and Cytogenetics

Year:

2003

Language:

english

File:

PDF, 516 KB

english, 2003

25

Concomitant transient erythroblastopenia of childhood with neonatal hepatitis

Hiroshi Moritake, Fumio Hidaka, Sachiyo Kamimura, Hitomi Kojima, Hidemi Shimonodan, Hiroyuki Nunoi

Journal:

Pediatrics International

Year:

2012

Language:

english

File:

PDF, 1.74 MB

english, 2012

26

Cytomegalovirus retinitis as an adverse immunological effect of pulses of vincristine and dexamethasone in maintenance therapy for childhood acute lymphoblastic leukemia

Hiroshi Moritake, Sachiyo Kamimura, Hitomi Kojima, Hidemi Shimonodan, Masako Harada, Takako Sugimoto, Nobuhisa Nao-i, Hiroyuki Nunoi

Journal:

Pediatric Blood & Cancer

Year:

2012

Language:

english

File:

PDF, 729 KB

english, 2012

27

Study on the Superoxide-Producing Enzyme of Eosinophils and Neutrophils—Comparison of the NADPH Oxidase Components

Akimasa Someya, Kousuke Nishijima, Hiroyuki Nunoi, Seiji Irie, Isao Nagaoka

Journal:

Archives of Biochemistry and Biophysics

Year:

1997

Language:

english

File:

PDF, 381 KB

english, 1997

28

Synthetic Peptides Corresponding to Various Hydrophilic Regions of the Large Subunit of Cytochrome b558Inhibit Superoxide Generation in a Cell-Free System from Neutrophils

Mi-Yeoun Park, Shinobu Imajoh-Ohmi, Hiroyuki Nunoi, Shiro Kanegasaki

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 173 KB

english, 1997

29

Uncompetitive Inhibition of Superoxide Generation by a Synthetic Peptide Corresponding to a Predicted NADPH Binding Site in gp91-phox,a Component of the Phagocyte Respiratory Oxidase

Tomoko Tsuchiya, Shinobu Imajoh-Ohmi, Hiroyuki Nunoi, Shiro Kanegasaki

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 61 KB

english, 1999

30

A missense mutation of the Toll-like receptor 3 gene in a patient with influenza-associated encephalopathy

Fumio Hidaka, Susumu Matsuo, Tatsushi Muta, Koichiro Takeshige, Tomoyuki Mizukami, Hiroyuki Nunoi

Journal:

Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 339 KB

english, 2006

31

Multicenter prospective evaluation of a novel rapid immunochromatographic diagnostic kit specifically detecting influenza A H1N1 2009 virus

Shoji Kawachi, Takeji Matsushita, Takeyuki Sato, Hiroyuki Nunoi, Hiroshi Noguchi, Setsuo Ota, Nobuko Kanemoto, Keigo Nakatani, Toshihiro Nishiguchi, Akihiko Yuge, Hideaki Imamura, Hirotake Kitajima, K

Journal:

Journal of Clinical Virology

Year:

2011

Language:

english

File:

PDF, 436 KB

english, 2011

32

Translocation of guinea pig p40-phox during activation of NADPH oxidase

Akimasa Someya, Isao Nagaoka, Hiroyuki Nunoi, Tatsuhisa Yamashita

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

1996

Language:

english

File:

PDF, 931 KB

english, 1996

33

Leukocyte adhesion deficiency: Identification of novel mutations in two japanese patients with a severe form

Shinya Matsuura, Fumio Kishi, Masato Tsukahara, Hiroyuki Nunoi, Ichiro Matsuda, Kunihiko Kobayashi, Tadashi Kajii

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 859 KB

english, 1992

34

Role of Mg2+ in activation of nadph oxidase of human neutrophils: Evidence that Mg2+ acts through G-protein

Kunihiko Aoyagi, Koichiro Takeshige, Hideki Sumimoto, Hiroyuki Nunoi, Shigeki Minakami

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 504 KB

english, 1992

35

Modulation of degranulation and superoxide generation in human neutrophils by unsaturated fatty acids of odd carbon numbers

Akiko Ishida-Okawara, Tomoko Tsuchiya, Hiroyuki Nunoi, Satoshi Mizuno, Kazuo Suzuki

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1996

Language:

english

File:

PDF, 651 KB

english, 1996

36

Randomized controlled trial of single-agent glimepiride and pioglitazone in Japanese patients with type 2 diabetes: A comparative study

Nobuyuki Shihara, Masafumi Kitaoka, Nobuya Inagaki, Takashi Kadowaki, Seisuke Koumoto, Jo Satoh, Yasuo Terauchi, Kiyohide Nunoi, Yuichiro Yamada, Hiroyuki Sakamaki, Yutaka Seino

Journal:

Journal of Diabetes Investigation

Year:

2011

Language:

english

File:

PDF, 231 KB

english, 2011

37

Regulation of Receptors for Formyl-Chemotactic Peptide in Human Polymorphonuclear Leukocytes: Analysis of Chemotactic Dysfunction of Cord Blood Granulocytes

Journal:

Pediatrics International

Year:

1985

Language:

english

File:

PDF, 375 KB

english, 1985

38

Characterization of the GTP-dependent activation of the superoxide-producing NADPH oxidase in a cell-free system of pig neutrophils

Lixin Yu, Koichiro Takeshige, Hiroyuki Nunoi, Shigeki Minakami

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1993

Language:

english

File:

PDF, 837 KB

english, 1993

39

Severe hypoplasia of lymphoid tissues in Mo1 deficiency

Hiroyuki Nunoi, Yasuhide Yanabe, Shigenori Higuchi, Hiroyuki Tsuchiya, Jiro Yamamoto, Ichiro Matsuda, Makoto Naito, Kiyoshi Takahashi, Kyoko Fujita, Masashi Uchida, Kunihiko Kobayashi, Masayoshi Jono,

Journal:

Human Pathology

Year:

1988

Language:

english

File:

PDF, 7.75 MB

english, 1988

40

Nephrotic syndrome complicated by idiopathic central diabetes insipidus

Konomoto, Takao, Tanaka, Etsuko, Imamura, Hideaki, Orita, Mayuko, Sawada, Hirotake, Nunoi, Hiroyuki

Journal:

Pediatric Nephrology

Year:

2014

Language:

english

File:

PDF, 134 KB

english, 2014

41

rhG-CSF for Shwachman's syndrome

Adachi, Naoto, Tsuchiya, Hiroyuki, Nunoi, Hiroyuki, Higuchi, Shigenori, Akaboshi, Izumi, Chikazawa, Shouji

Journal:

Year:

1990

Language:

english

File:

PDF, 155 KB

english, 1990

42

Unusual case of diffuse connective tissue disease with nodule formations in muscle, lung, kidney and brain

Nobukuni, Yoshitaka, Miike, Teruhisa, Ohtani, Yoshinobu, Tsuchiya, Hiroyuki, Nunoi, Hiroyuki, Hattori, Shinzaburo, Matsuda, Ichiro

Journal:

Brain and Development

Year:

1986

Language:

english

File:

PDF, 1.28 MB

english, 1986

43

A Heterozygous Mutation of β -Actin Associated with Neutrophil Dysfunction and Recurrent Infection

Hiroyuki Nunoi, Tsuyoshi Yamazaki, Hiroyuki Tsuchiya, Seishi Kato, Harry L. Malech, Ichiro Matsuda and Shiro Kanegasaki

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.25 MB

english, 1999

44

Clinical characteristics and genetic analysis of childhood acute lymphoblastic leukemia with hemophagocytic lymphohistiocytosis: a Japanese retrospective study by the Kyushu–Yamaguchi Children’s Cancer Study Group

Moritake, Hiroshi, Kamimura, Sachiyo, Nunoi, Hiroyuki, Nakayama, Hideki, Suminoe, Aiko, Inada, Hiroko, Inagaki, Jiro, Yanai, Fumio, Okamoto, Yasuhiro, Shinkoda, Yuichi, Shimomura, Maiko, Itonaga, Nobu

Journal:

International Journal of Hematology

Year:

2014

Language:

english

File:

PDF, 439 KB

english, 2014

45

Proposed strategy for the use of high-dose chemotherapy with stem cell rescue and intrathecal topotecan without whole-brain irradiation for infantile classic medulloblastoma

Yamada, Ai, Moritake, Hiroshi, Kamimura, Sachiyo, Yamashita, Shinji, Takeshima, Hideo, Nunoi, Hiroyuki

Journal:

Pediatric Blood & Cancer

Year:

2014

Language:

english

File:

PDF, 2.23 MB

english, 2014

46

Prevalence of Inherited Myeloperoxidase Deficiency in Japan

Nunoi, Hiroyuki, Kohi, Fumikazu, Kajiwara, Hideki, Suzuki, Kazuo

Journal:

Microbiology and Immunology

Year:

2003

Language:

english

File:

PDF, 131 KB

english, 2003

47

Risk Parameters of Fulminant Acute Respiratory Distress Syndrome and Avian Influenza (H5N1) Infection in Vietnamese Children

Kawachi, Shoji, Luong, San Thi, Shigematsu, Mika, Furuya, Hiroyuki, Phung, Thuy Thi Bich, Phan, Phuc Huu, Nunoi, Hiroyuki, Nguyen, Liem Thanh, Suzuki, Kazuo

Journal:

The Journal of Infectious Diseases

Year:

2009

Language:

english

File:

PDF, 331 KB

english, 2009

48

Evaluation of Systemic Inflammatory Responses in Neonates with Herpes Simplex Virus Infection

Kawada, Jun‐ichi, Kimura, Hiroshi, Ito, Yoshinori, Ando, Yoshihiro, Tanaka‐Kitajima, Naoko, Hayakawa, Masahiro, Nunoi, Hiroyuki, Endo, Fumio, Morishima, Tsuneo

Journal:

The Journal of Infectious Diseases

Year:

2004

Language:

english

File:

PDF, 116 KB

english, 2004

49

Novel human homologues of p47 phox and p67 phox participate in activation of superoxide-producing NADPH oxidases.:

Takeya, Ryu, Ueno, Noriko, Kami, Keiichiro, Taura, Masahiko, Kohjima, Motoyuki, Izaki, Tomoko, Nunoi, Hiroyuki, Sumimoto, Hideki

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 552 KB

english, 2015

50

Sporadic paraganglioma caused by de novo SDHB mutations in a 6-year-old girl

Imamura, Hideaki, Muroya, Koji, Tanaka, Etsuko, Konomoto, Takao, Moritake, Hiroshi, Sato, Takeshi, Kimura, Noriko, Takekoshi, Kazuhiro, Nunoi, Hiroyuki

Journal:

European Journal of Pediatrics

Year:

2016

Language:

english

File:

PDF, 517 KB

english, 2016

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